Chemistry of Medical Isotopes and Molecular Imaging Probes and Therapeutics

Molecular imaging is an exciting and rapidly expanding field that is yielding major scientific and medical breakthroughs. At the heart of the field is research and development into the chemistry and chemical biology of medical isotopes and molecular imaging probes.

In the Valliant group we seek to develop new synthetic methods and technology-based platforms that facilitate the preparation and discovery of novel molecular imaging probes. Our work includes innovations in coordination chemistry, organic synthesis and in chemical biology to create agents that have high affinity for proteins specifically associated with diseases like cancer.

valliantscan
Positon Emission Tomography (PET) scan of a cancer patient. The intense white area indicates the location and biological activity (glucose metabolism) of a tumor.

Molecular imaging methods use probes – molecules that seek out the disease markers and that emit a signal that can be detected by an imaging device:

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The Valliant research group focuses on nuclear, optical and ultrasound imaging.

To create new molecular imaging probes requires new chemistry:

 

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